Leese, G. P., Soto-Pedre, E., Donnelly, L. A.: Liothyronine use in a 17 year observational population-based study - the tears study

Abstract

The aim of the study was to look at adverse outcomes for patients on liothyronine compared to l-thyroxine. Some trials have examined the relative merits of liothyronine but none have looked at adverse outcomes in large numbers.

For patients taking long-term liothyronine we did not identify any additional risk of atrial fibrillation, cardiovascular disease or fractures. There was an increased incident use of antipsychotic medication during follow-up

Keywords

• cardiovascular diseases
• thyroid function
• liothyronine
• l-thyroxine