Publication at Faculty of Medicine in Hradec Králové |
2017
Abstract
Subcorneal pustular dermatosis is a rare, chronic, relapsing pustular eruption characterized by subcorneal pustules that contain neutrophils on histopathology. It was first described by Sneddon and Wilkinson in 1956.
It is more common in middle-age and older woen but has been reported to occur also in children. Clinical findings are discrete, flaccid pustules or grouped vesicles that present predominantly on the flexor surfaces.
In rare cases, unusual involvement of the face, palms and soles has been described. The pathogenesis of this clinical entity is still controversial.