Abstract
Cardiovascular diseases are still the leading cause of morbidity and mortality in developed countries. Only by complex reviewincluding all risk factors of atherosclerosis are we able to optimally reduce the risk of the patient.
Combining drug group enablesthe patient to achieve a certain target value, and obtain improve results due to increasingly strict and clear recommendations.With the increasing amount of pharmacological therapy, the patient adherence to physical therapy unfortunately decreases.Fixed combinations are the most perspective solution for patient adherence to a drug therapy. Nowadays, there are not onlyfixed combinations (especially) for a single risk factor, or a group of factors, available on the market, but also new drugs, whichcontain substances that affect multiple risk factors for atherosclerosis.