Publication at Faculty of Medicine in Hradec Králové |
2017
Abstract
Diabetes mellitus is associated with cognitive impairment which may convert to vascular or neurodegenerative demantia. Impairment of cognitive functions affects patients with type 1 and especially 2 diabetes, with a number of vascular, metabolic and psychosocial factors involved in its development.
As hyperglycemia and hypoglycemia also play an important role, important is the correct strategy of diabetes therapy which utilizes a combination of metformin with medern safe antidiabetecs (incretin drugs, gliflozins, insulin analogues). It seems that some antidiabetic drugs (metformin, incretin drugs) and nasal form of application of insulin could improve cognition in diabetics.