Development of a Tube Nebulizer for Microflow Atmospheric Pressure Chemical Ionization Mass Spectrometry
2017
Abstrakt
A novel nebulizer for microflowatmospheric pressure chemical ionization mass spectrometry was developed. It consisted of a tube with analyte-transporting fused silica capillary inside.
The terminal part of the tubewas resistively heated using a coiled resistance wire. Optimal nebulizer parameters and construction setup were investigated to fully demonstrate its versatility.
Corundum appeared to be a more suitablematerial than quartz for fabrication of the tube nebulizer.The lowest analyte flowrate investigatedwas 1.0 μl/min with an excellent signal stability reached.