Purpose of the study - The aim of our study was to evaluace the impact of Neodoplpasse infusion postoperatively on the clot forming process
Abstract
Methods: Since October 2014 until June 2015, we prospectively enrolled 207 patients who were admitted to our intensive care unit due to the postoperative care. All the patients underwent hip, knee or column surgery and abdominal surgery from laparotomia.
During 90 minute intravenous infusion, Neodolpasse 250 mL was administered to all the pacients The blood samples were taken before, 2 and 4 hours after the Neodolpasse infusion to rotational tromboelastometry evaluation. Results: Despite of a large heterogenity of our cohort in age, lenght and type of surgery, we did not observe any statistically significant differences in the clot forming, development and maximal strenght of the blood clot following 250 mL of Neodolpasse infusion in a postoperative period.
Conclusion: According to our results, Neodolpasse infusion postoperatively does not impact the clot forming, kinetics and strenght of the blood clot. The limitation of our study could be a small cohort of patients.