Abstract
Context Botulinum toxin A and B is approved for treatment of many diseases, and we can read many papers experimenting with others possibilities. Use of botulinum toxin is a rel-atively new option with little or no pre-gradual training in the dentistry.
This article aims to summarise current knowledge in this emerging field. Objective This article aims to summarise current knowledge in this emerging field.
Data Sources A search of MEDLINE, EMBASE, bibliographies of published systematic reviews, and the Cochrane trial registries between 1966 and June 10, 2016. Study Selection Randomized controlled trials comparing botulinum toxin A with placebo or other interventions were preferred, but for many emerging indication we used non-randomized studies as well to inspire further studies.
Data Extraction Data were abstracted and quality assessed by 1 reviewer. Data Synthesis We have little-randomised data to quantify the effect of botulinum toxin in a majority of indications in dentistry precisely.
Conclusion The rapid development of the botulinum toxin application brings new possi-bilities for treatment by dentist alone or in cooperation with other specialists. Besides the above-verified evidence-based indications, there are quickly appearing new and new case studies that need to be monitored and possibly applied.
But we have very few ran-domised studies to make final guidelines in many indications, so further scientific works are very needed. Botulinum toxin should be part of undergraduate and postgraduate teaching.