Testicular Cancer in Monozygotic Twin Brothers with Urticaria Pigmentosa

Abstract

Urticaria pigmentosa (UP) is the most common variant of cutaneous mastocytosis. The occurrence of UP in twins is rare.

We have described a case of monozygotic twin brothers, with the first signs of UP at the age of 4 months and now present the development of their disease until 43 years of age, with the additional appearence of testicular cancer at age 30.

Keywords

• indolent systemic mastocytosis
• d816v mutation burden
• kit d816v
• imatinib