Lymphogranuloma venereum (LGV), a largely tropical or sub-tropical sexually transmitted disease (STD) that is rare in Europe, has emerged in the Czech Republic. The cause is Chlamydia trachomatis, in particular its invasive serovars L1, L2, and L3.
Similarly to other EU countries, most LGV cases have been reported in men who have sex with men. Co-infections with other STDs such as HIV disease, syphilis, gonorrhoea, and viral hepatitis C (VHC) are often observed.
LGV proctitis is a challenging diagnostic entity. Chlamydia trachomatis isolates need to be referred, after prior arrangement, to the National Reference Laboratory for Chlamydia of the National Institute of Public Health for serovar determination using molecular genetic methods.