Targeting mast cells and Basophils in Allergy and beyond: Emerging Concepts

Abstract

Since the times of P. Ehrlich, F.

D. von Recklinghausen, and O.Westphal, the research on mast cells and basophils made significant progression towards the recognition of their involvement in antimicrobial functions and of their role in mobilizing inflammation in wound healing, allergy, and autoimmunity. However, the role of mast cells in normal physiology is still poorly understood.

Keywords

• Immune cells
• Mastocytosis
• Connective tissue cells
• Leukocytes
• White blood cells
• Granulocytes
• Degranulation
• Myeloid cells