Childhood narcolepsy and autism spectrum disorders: four case reports

Abstrakt

Background: Childhood narcolepsy is associated with various emotional, behavioural and cognitive dysfunctions as well as with psychiatric and neurodevelopmental disorders: anxiety, depression, attention deficit hyperactivity disorder and psychosis. A relationship between these conditions is unclear - comorbidity or similar pathophysiological mechanisms can be suggested.

Objective: We reported four children with narcolepsy type 1 (NT1) and autism spectrum disorder (ASD) - Asperger syndrome (AS). Results and Conclusion: To the best of our knowledge co-occurrence of NT1 and AS has not been described in the literature as noted in this report. (C) 2018 Elsevier B.V.

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Klíčová slova

• Narcolepsy type 1
• Asperger syndrome
• Autism spectrum disorders
• Comorbidity
• Hypocretin