Abstract
Magnetic resonance imaging (MRI) is the most important paraclinical test for diagnostics of multiple sclerosis (MS). Equally important role of MRI is a prediction of future clinical status and lifelong monitoring of disease activity and response to its treatment.
MRI also provides important information at the unveiling of pathological processes which occur in MS. New chapter on signal characteristics in the MR image for white matter illness was added, the Patient Monitoring Passage expanded into clinical practice at the MR Radiodiagnostic Clinic of the 1st Faculty of Medicine, the first in the world in 2009.
The book introduces the reader to the concept of disease free concept, NEDA 3 (no evidence of disease activity), NEDA 4, where MR judgment is included. The chapter on differential diagnostics is, among others, divided into physiological findings and diseases with a similar MR finding as in MS, and a great deal of attention is paid to rare opportunistic infections - progressive multifocal leukoencephalopathy that may be associated with treatment in MS patients.
Considerable space is also devoted to neuromyelitis optica, where changes in diagnostic criteria have occurred. A group of congenital defects and metabolic disorders (myelinating disorders) are also included separately.