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Secondary immunodeficiencies induced by biologic therapy

Publication at Second Faculty of Medicine |
2018

Abstract

Secondary immunodeficiency represents a wide range of immune disorders that are triggered by a number of causes. These disorders started to get attention particularly lately with the onset of biologic therapy, when particularly B cell depleting therapies lead to a significant secondary antibody deficiency in a subset of patients.

The article summarizes the causes and nature of secondary antibody deficiencies and deals with the immunological aspects of diagnosis and treatment of these conditions.