Verification of lag-time of pellets with controlled release of glucose during various physical activities
Abstrakt
Prevention of hypoglycemia is a obligation in physical activities of people with Type 1 Diabetes Mellitus (T1D). We used pellets with sequential release of glucose to prevent harmful need to eat in the course of physical exercise.
The work verified the stability of 240minute lag-time of the pellets under the conditions of varied long-lasting physical activity in adolescents and young adults with T1D, using C-13 breath test. A systemic programme of specific physical activity to verify an impact of physical load and of aerobic/anaerobic and mixed exercise on the lag-time of pellets in real life.
We designed a protocol of various forms and courses of motion within 3 consecutive days. The subjects' responses to exercise were monitored by heart rate and continuous glucose monitoring, C-13-glucose breath test was used to assess pellets behaviour during sport.
Eight boys with T1D without chronic complications aged 13 to 20 years (weight 68.8 +/- 16.3 kg, height 173.5 +/- 11.5 cm, BMI 22.25 +/- 4.55 kg/m(2) were included in the study. Ruffier fitness test and the measurement of resting heart rate determined their physical readiness.
Three-day programme graded in intensity consisted of atypical sports, activities with cognitive processes, speed-endurance motion with high physical and mental demands and with accented fluctuations in heart rate. Our study has shown the stability of the lag-time of the pellets under various physical activities of adolescents and young adults with T1D.
The programme of physical activity traced the needs and accents of the research project.