Abstract
Melanoma of the urethra, or melanomas originating from the gynecological tract, are extremely rare and aggressive malignant tumors, with high metastatic potential and a poor prognosis, affecting almost exclusively elder female patients. The aim of this case report is to present the case of a patient with urethral and bladder melanoma metastasis from a previously treated primary melanoma of the vulva.
Radical cystourethrectomy and Bricker-Nesbit ureteroileostomy and bilateral extended pelvic lymphadenectomy were performed. Histology report confirmed melanoma invading the urethra and bladder, all removed lymphatic nodes were negative.
On the 6-month follow-up PET-CT there was no evidence of residual disease. We concluded that in the presence of such a suspicious urethral lesion, prompt diagnosis to differentiate from other benign lesions and early radical management with careful post-operative follow-up schedules should be the standard treatment.