Publication at Faculty of Medicine in Hradec Králové |
2019
Abstract
Multiple sclerosis (MS) is a chronic autoimmune neurodegenerative disease that affects predominantly young females of childbearing age.Historically, women with MS were discouraged from having children as pregnancy was thought to negatively affect the disease course. However, over the past few decades, studies have shown that the opposite is true.
Thanks to scientific research and modern therapeutic approaches many women remain chlinically and radiologically stable and they can give birth to healthy babies. Unfortunately, there is limited information regarding the safety of disease-modifying drugs (DMD) during pregnancy.
The paper deals with the possible risks od individual DMD used for MS in early pregnancy.