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Update of Cardiovascular Outcome Trials (CVOTs) in Diabetes - CVOT Summit 2018

Publication at First Faculty of Medicine |
2019

Abstract

The 4th Cardiovascular Outcome Trial (CVOT) Summit of the Diabetes & Cardiovascular Disease (D&CVD) EASD Study Group was held in Munich on 25 and 26 October 2018. As in previous years, this summit served as reference meeting for in-depth discussions on the topic of recently completed and presented CVOTs.

This year, focus was placed on the CVOTs CARMELINA, DECLARE-TIMI 58 and Harmony Outcomes. Trial implications for diabetes management and the impact of the new ADA/EASD consensus statement treatment algorithm were highlighted for diabetologists, cardiologists, endocrinologists, nephrologists and general practitioners.

Discussions evolved from CVOTs to additional therapy options for heart failure (ARNI), knowledge gained for adjunct therapy of type 1 diabetes and, on the occasion of the 10 year anniversary of the FDAs "Guidance for Industry": Should CVOTs be continued and/or modified? The 5th Cardiovascular Outcome Trial Summit will be held in Munich on 24 and 26 October 2019 (www.cvot.org).