2-Morpholino-3,4-dihydroquinazolin-4-one derivative with aromatic substituents at the 8- position, process for its preparation and use
Abstract
The present invention relates to novel 2-morpholin-4-yl-3,4-dihydroquinazolin-4-one derivatives having a substitution at the 8- position, to a process for their preparation and to their use in medicine. Selective DNA-PK inhibitors are potentially useful as a means of sensitizing tumor cells to chemotherapy and radiotherapy.