Publication at First Faculty of Medicine |
2019
Abstract
Biological drugs have been extensively involved in the treatment of a number of diseases in recent years and have often made incurable chronic mutilizing diseases treatable, and even sometimes curable, by treatment, changing the fate of millions of patients. However, biological drugs, by their mechanism of action, can also interfere with the immune processes involved in the defense against infections and can cause an imbalance of the immune system, which itself leads to the initiation of new immunopathological states.
This should always be considered in the indication and management of this treatment.