Czech-Greek relations in the period of the Middle Ages (until 1453 - when the Ottoman Turks took over Constantinople) have taken the forms of political, ecclesiastical, and cultural contacts between the Czech lands and the ethnically and politically "Greek" core of the Byzantine Empire; the later, with the ethnically "Greek" parts of the Ottoman Empire. Since the 19th century; to wit, after the genesis of the modern, independent Greek state (Kingdom of Greece, 1830-1832), Czech-Greek contacts gradually transformed into relations between two modern nations - Czechs and Greeks.
In the years 1918-1992 (with an interruption between 1939-1945) they developed within the broader framework of international Czechoslovak-Greek relations. Since 1993 they play out as relations between the independent Czech Republic and the Hellenic Republic.