Boron-doped diamond electrode fabricated by microwave plasma enhanced chemical vapour deposition process with linear antenna delivery for neurotransmitters sensing
Abstrakt
Morphological, spectral and electrochemical characterization of boron-doped diamond (BDD) electrode deposited by microwave plasma enhanced chemical vapour deposition process with linear antenna delivery apparatus was performed by scanning electron microscopy, Raman spectroscopy and cyclic voltammetry. Fast electron transfer kinetics was confirmed for studied redox markers at as-deposited hydrogen-terminated BDD surface (H-BDD) and also after applying anodic activation resulting in oxidized surface.
Moreover, the voltammetric behaviour of dopamine, an essential biologically active compound of which abnormal levels in physiological fluids are associated with neurological disorders, was examined. Due to the substantial fouling of the H-BDD film during dopamine oxidation process, anodically activated BDD film was chosen to perform further experiments with this neurotransmitter.
Concentration dependency for dopamine in phosphate buffer pH = 7.4 was constructed and detection limit of 1.22 μmol L(-1) was achieved.