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Inherited C2-complement deficiency: variable clinical manifestation (case reports and review)

Publication at Faculty of Medicine in Hradec Králové |
2020

Abstract

C2 deficiency represents the most frequent type of a complement deficiency. Clinical manifestation includes infections caused by encapsulated bacteria (Streptococcus pneumoniae, Neisseria meningitidis) such as meningitis, gonitis, pneumonia or septicaemia.

A causative treatment has not been available yet A prophylactic vaccination and/or a long-term antibiotics prophylaxis are recommended.