Abstract
Due to numerous idiosyncratic features, a profound variety in the level of development and in the nature of regional innovation systems is often acknowledged. This paper has aimed to contribute to existing research by unraveling mutual relationships among knowledge bases, R&D structure and innovation performance of European regions.
Our analysis showed that the differences among the European regions in their prevailing knowledge base and in the absolute and relative sizes of key segments of R&D systems are systematic and mutually interwoven. Generally, advanced regions are often typified by the lowest share of synthetic knowledge base and either by a dominance of the private R&D or by a relatively balanced structure between private and public R&D, while the opposite holds for lagging regions.