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The clinical and biological characteristics of NUP98-KDM5A in pediatric acute myeloid leukemia

Publikace na 2. lékařská fakulta |
2021

Tento text není v aktuálním jazyce dostupný. Zobrazuje se verze "en".Abstrakt

Pediatric acute myeloid leukemia (AML) is a rare, heterogeneous disease, characterized by recurrent cytogenetic and molecular aberrations. Genetic aberrations are the most important prognostic factor, besides early response to treatment.

Here, we present the results of a collaborative study between the Children's Oncology Group (COG) and European AML study groups, aimed to define the biological and clinical characteristics of AML patients carrying NUP98-KDM5A outside acute megakaryoblastic leukemia.