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Multiple risk factors intervention in patients with type 2 diabetes: current state and perspectives

Publication at First Faculty of Medicine |
2020

Abstract

The total cardiovascular (CV) risk in patients with type 2 diabetes is a continuum of action of particular risk factors (RF) and their interconnected pathophysiological relationships caused mainly by insulin resistance. These determine the development, progression and manifestation of both micro- and macrovascular complications.

Risk factors for atherosclerotic CV disease never occur alone, but typically accumulate. Therefore, it is always necessary to actively look for them and then determine the total CV risk of the individua!.

Appropriately chosen systematic treatment intervention - a combination of regimen measures, comprehensive and long-term cardioprotective medication - can lead to satisfactory control of partial monitored parameters and thus a reduction in CV mortality and morbidity. The aim ofthis paper is to provide a relatively brief overview of modem possibilities of influencing CV risk in patients with diabetes and associated metabolic comorbidities.