Triazoles (e.g., tebuconazole, penconazole, propiconazole and cyproconazole) are frequently used agrochemicals against fungal pathogens. Primarily they were designed to block 14alpha-demethylase of fungal pathogens 1.
However, they affect also aromatase 2 and possibly other enzymes of the broad family of cytochrome P450 enzymes of non-target organisms in soil as well as plants. The effect of triazolic fungicide on the environmental system in the meaning of the soil-plant system is not well understood.
As was found previously by our group 3, the interactions in cocktails with other biologically active chemicals are highly expected. We have to consider also the impact of triazoles in their mixtures because of their joint application or consecutively we have to consider also the group effects of triazoles.
This contribution summarized almost 10-years research of triazoles and their impact on the environmental and biochemical systems.