Abstrakt
Primary bone lymphoma (PBL) is a rare disease that accounts for about 5% of all extranodal lymphomas, and the most common subtype is a non-Hodgkin diffuse large B-cell lymphoma (DLBCL) represent approximately 50-92% of PBLs [1]. Much more common plasma cell tumors are not included in this entity.
The lesion may be in a single focus or disseminated, since polyostotic disease occurs in approximately 15-20% of patients. PBL should be distinguished from much more common secondary bone involvement in the case of nodal or other extranodal lymphoma, whereas these may be indistinguishable.
The most frequent sites of PBL are the femur, spine, and pelvic bones. PBL of the skull is uncommon.
Herein, we present a rare case of a female patient with primary DLBCL of the parietal bone. 70-year-old Caucasian woman presented with a palpable slightly painful induration on the calva. The lesion was found in a control PET scan performed due to breast carcinoma in the patient's history.
The subtype of breast carcinoma was not known at the recent presentation. The patient underwent a right-sided mastectomy and combined adjuvant radiotherapy, hormonal therapy, and chemotherapy with doxorubicine and endoxan because of mammary carcinoma resected 14 years prior to recent presentation.
