Abstract
Objective: To summarize recent data and knowledge of secondary prevention of the recurrence of intrauterine adhesions in patients with Asherman's syndrome. Methods: Analysis of literature evidence and clinical experience of the authors.
Results: Asherman's syndrome is iatrogenic disease with problematic therapy. One of the basic issues is a need for repeated surgical interventions since the recurrence of adhesions is very frequent.
Secondary prevention is a crucial factor for successful therapy in these patients. The methods applied include second--look hysteroscopy, hormonal treatment and different types of barriers.
To compare their efficacy is difficult and the results of meta-analysis are contradictory. Conclusion: There are many different possibilities of secondary prevention of the recurrence of intrauterine adhesions; unfortunately, none of them is perfect.
The usage of solid or semi-solid barriers in combination with the support of endometrium regeneration with hormonal therapy seems most reasonable.