Patient with angioedema - what a general practitioner should know?

Abstract

Angioedema is self-limited localized subcutaneous or submucosal swelling due to enhanced vascular permeabilitity. There are two main mediators involved in angioedema pathogenesis - histamine and bradykinine.

Distinguishing between histaminergic and bradykinin mediated angioedema is crucial for choosing an effective treatment.

Keywords

• angioedema
• bradykinin
• histamine
• urticaria
• C1 inhibitor