The optimal concentration of glucose in the blood - glycemia is vital for many organs. The most important is the brain.
Glycemia is affected by several hormones and cellular signaling molecules. Hypoglycemia is a potent stress factor for the body which is prevented by an acute regulatory and long-term adaptation reaction.
By rapidly changing hypoglycemia to hyperglycemia, we reverse the patient's life-threatening condition, but reperfusion of the brain with glucose-rich blood has a somewhat even more negative effect on neurons. Treatment of hypoglycemia should be gradual and careful from this point of view.