Genetic influences in the formation of nasal polyps

Abstract

The cloning of the CFTR gene has led to the identification of several mutations that cause cystic fibrosis (CF). The clinical phenotype of this disease is diverse, and includes recurrent nasal polyps.

Polyposis nasi is a poorly understood condition, but genetic factors may be important in pathogenesis. We have analysed nasal polyps for the presence of different CFTR mutations.

Keywords

• nasal polyps