Abstract
Human papillomavirus (HPV) infection is the most common sexually transmitted infection. Persistent HPV infection has been repeatedly associated with the development of anogenital and oropharyngeal cancers and genital warts.
The prevalence of HPV infection appears to be twice as high in pregnant persons compared to non-pregnant persons. In addition, various studies suggest a negative effect of HPV infection on the course and complications of pregnancy.
To date, millions of doses of HPV vaccine have been administered worldwide. Unintentional administration of the HPV vaccine during pregnancy occurs most often in fertile young women, who are often unaware of their pregnancy at the time.
The HPV vaccine has not been approved for pregnant persons and is therefore not recommended. If unintentionally administered during pregnancy, it is recommended to delay the remaining doses of the vaccine until after delivery.
On the other hand, according to current scientific evidence, there is no link between HPV vaccination before or during pregnancy and adverse pregnancy outcomes. No increased incidence of fetal birth defects has been observed after vaccination and termination of pregnancy is not warranted in this case.