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Computational modeling of blood flow from medical images

Publikace na Matematicko-fyzikální fakulta |
2023

Tento text není v aktuálním jazyce dostupný. Zobrazuje se verze "en".Abstrakt

Medical imaging techniques play a crucial role in acquiring non-invasive information about physiological processes within the human body. One such technique is 4D phase-contrast magnetic resonance imaging (4D PC-MRI), which enables the measurement of blood flow velocity fields.

However, the accuracy of velocity field estimation is often limited due to the presence of noise in the acquired images. In this presentation, we introduce an improved technique tailored for situations involving significant variability of flow velocities in 4D PC-MRI images.

Our approach is based on the Optimal Multiple Motion Encoding (OMME) method, which requires a minimum of two measurements using different velocity encoding parameters (vencs). By performing a single measurement using a large venc, phase wraps in the results can be eliminated, but the noise level remains high as it is proportional to the venc.

Conversely, selecting a lower venc reduces the noise level but increases the number of wrapped voxels. By carefully selecting appropriate vencs, the OMME method effectively combines both measurements, resulting in phase wrap-free images with low noise levels.

However, using a ratio of low venc over high venc that is too small introduces another type of noise in the resulting image. To address this, we propose an improvement by incorporating a wavelet transform in the time domain, which exploits the temporal characteristics of the artifacts present in the noisy image.

Using this method, we were able to obtain better reconstruction of the velocity field both on synthetic data and on in-vivo data.