Background: The differential diagnosis of many nerodegenerative disorders depend primarily on clinical symptoms together with imaging methods. Recently, increased importance has been placed on the use of biomarkers for diagnosing various neurodegenerative disorders.
Objective: To assess the feasibility of tau-protein, phosphorylated tau-protein, beta-amyloid 42 (Abeta42), and 14-3-3 protein as biomarkers for diagnosis several neurodegenerative diseases complicated by cognitive deficits.