Biological prognostic markers in chronic lymphocytic leukemia

Abstrakt

The specific role of selected prognostic parameters (mutational status of IgVH genes, cytogenetic aberations, ZAP70 and CD38 expression) is summarized.

Klíčová slova

• chronic lymphocytic leukemia
• IgVH mutational status
• cytogenetic aberrations
• FISH
• p53
• ZAP-70
• CD38
• angiogenesis