Ultra high performance liquid chromatography tandem mass spectrometric detection in clinical analysis of simvastatin and atorvastatin

Abstrakt

Selective and sensitive method for the determination of simvastatin, atorvastatin and their metabolites was developed using UHPLC-MS/MS technique for clinical purposes.

Klíčová slova

• atorvastatin
• simvastatin
• hemodialysis
• UPLC
• tandem mass spectrometry
• bio-analytical method