Pentraxin 3 is the first detected and so far the most important protein from the recently recognized group called the long pentraxins. The structure and function of PTX3 resembles in many aspects that of the short or classical pentraxins, i.e.
C-reactive protein and the serum amyloid P component. There are, however, several important differences between the two groups of pentraxins that will be mentioned in more detail in the article.
This review article deals with the physiopathologic importace of pentraxin 3 as has been gained on the basis of the most up-to-date information.