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Topical duodenal and gastric mucosal production of interleukin-1beta, interleukin-6, interleukin-8, tumour necrosis alpha and interleukin-2-soluble receptor in Helicobacter pylori positive and negative patients

Publication at First Faculty of Medicine |
2004

Abstract

Pathogenesis of Helicobacter pylori (Hp) gastritis and duodenitis has not been fully explained yet. Aim of this project was to study topical duodenal and gastric cytokine production by means of ex-vivo in-vitro culture.

A total number of 85 biopsy specimens were taken during routine gastroscopy from gastric and duodenal mucosa in 17 persons (6 men, 11 women,21?74 years old).