Abstract
Primary coronary angioplasty with stent is an optimal treatment in patients with acute infarction myocardium with elevations of section ST on ECG within 12 hrs after the onset. Randomized studies proved a decrease in mortality, reinfarctions and strokes after this treatment, compared to treatment by thrombolysis.
Lower mortality rate was proven also in a subgroup of patients transported to PCI. The difference is distinct mainly in patients treated between 3rd and 12th hour after the infarction.
According to TIMI classification, the grade of stream flow through the coronary artery plays a great role. The question of facilitated primary PCI remains thus up-to-date. While a mechanical operation ensures immediate reperfusion by restoration of the flow through epicardial artery, the medication facilitation should improve the perfusion in tissues and ensure a permanent reperfusion.
