Publication at First Faculty of Medicine |
2003
Abstract
Bone is a common site of metastatic disease and is the most common site of metastatic spread in breast cancer and prostate cancer.The pain is themost important consequence of bone metastases and is present in most of the patients. Radiotherapy represents one of effective therapeutic options in the palliation of bone pain.
Currently, radiation may be delivered either by external irradiation (loco-regional, half-body) or intravenous administration of bone-seeking therapeutic radiopharmaceuticals as is Samarium-153-EDTMP. This radiopharmaceutical produces beta radiation, and is concentrated in areas of enhanced osteoblastic activity.