The aim of this study was to evaluate the characteristics of atrial myocardium in pulmonary veins from subjects with and without a history of atrial fibrillation. A total number of 43 human hearts obtained at autopsy were studied (27 men, 16 women, mean age 67 +- 8 years).
Sixteen subjects (group 1) had a history of atrial fibrillation (11 men, mean age 66 +- 10 years). The remaining 27 subjects (group 2) were without arrhythmia (16 men, mean age 68 +- 8 years).
The presence and morphology of the myocardial extensions were studied microscopically. In conclusion, a significant interindividual variability in the presence, arrangement, and thickness of atrial myocardial sleeves into PVs was revealed.
Patients with a history of atrial fibrillation were found to have longer and thicker myocardial extensions into the upper PVs, and this finding may have implications for the catheter ablation technique.