Scintigraphic Detection of Osteoblast Activity after Implantation of BAS-0 Bioactive Glass-Ceramic Material into Long Bone Defects
Abstract
20 patients, 14 male and 6 female, at average age 14 years (range, 8 to 24) operated for defects in the femur (11), tibia (5) or humerus (4) covered 11 juvenile bone cysts, 5 aneurysmal bone cyst, 2 non-ossifying fibroma and 2 fibrous dysplasia. Evaluation was carried out at 2 to 12 years (average 7 yrs) after surgery.
Of the 8 pts with filling of metaphyses, 6 had no subjective complaints and 2 reported transient pain. Of the 12 pts with implants in diaphyses, complaints were recorded in 9.
On radiography, 2 pts had a residual defect, others were free from any disease residue or recurrence. The implant was completely incorporated in all.
Three-phase bone radionuclide scans were also analysed. Stress accumulating at the interface of a rigid implant and bone tissue may result in pain, particularly in diaphyseal grafts, and is detected by scintigraphy.
Non-resorbable glass-ceramic materials are not suitable in this indication.