Sibutramine is a very effective antiobesitic drug in the present. It has weight reducing, global metabolic and antidiabetic effects.
To verify and to get the experiences with practical use of sibutramin in Type 2 diabetics in the Czech Republic the purpose of the clinical observation MERIDIOS I. Significant weight loss, diminished waist circumference and blood pressure, improvement of diabetes compensation and lower daily dose of oral hypoglycemic agents were observed in obese Type 2 diabetics after 3 months therapy with sibutramine in the dose 10 or 15 mg per day.