Bone defects require reconstruction and use of bone grafts or bone substitutes to help healing of skeletal injuries. The iliac autologous graft remains the gold standard.
Autologous bone grafting, however, involves also certain complications. There are various methods how to use allografts, but they are connected with possible infectious and immunological problems.
Bone substitute materials are: metals and their alloys, artificial plastic materials, components and ceramics. The authors present a basic overview regarding the main groups of artificial bone substitutes, their properties and their benefit in orthopaedic surgery.
References to possible future development in this field of biological research are also included.