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Proteomic analysis of MOLT-4 cells treated by valproic acid

Publication at First Faculty of Medicine |
2007

Abstract

The effect of valproic acid (VA) on protein expression in human T-lymphocytic leukemia cells MOLT-4 was studied. VA is an inhibitor of histonedeacetylases and has a potential use as antitumor agent in leukemia treatment.

This study evaluates proteome changes after exposure to VA.