Pathological Complete Response in Advanced Gastrointestinal Stromal Tumor after Imatinib Therapy

Abstract

Gastrointestinal stromal tumor (GIST) is a rare neoplasm exhibiting, in most cases, mutations of c-kit. Recently it has been demostrated that a majority of GIST patients with c-kit mutations respond to therapy with imatinib, a c-kit tyrosine kinase inhibitor.

Keywords

• gastrointestinal stromal tumor
• imatinib
• pathological complete response