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publication
Inhibitory histondeacetylas, valproát a trichostatin A, jsou toxické pro neuroblastomové buňky a ovlivňují v těchto buňkách expresi cytochromů P450 1A1, 1B1 a 3A4
2009 |
Přírodovědecká fakulta, 1. lékařská fakulta, Fakulta tělesné výchovy a sportu, Matematicko-fyzikální fakulta
publication
Theoretical investigation of differences in nitroreduction of aristolochic acid I by cytochromes P450 1A1, 1A2 and 1B1
2012 |
Přírodovědecká fakulta
publication
Active Site Mutations as a Suitable Tool Contributing to Explain a Mechanism of Aristolochic Acid I Nitroreduction by Cytochromes P450 1A1, 1A2 and 1B1
2016 |
Přírodovědecká fakulta
publication
Serum Levels of Aryl Hydrocarbon Receptor, Cytochromes P450 1A1 and 1B1 in Patients with Exacerbated Psoriasis Vulgaris
2018 |
Lékařská fakulta v Hradci Králové, Farmaceutická fakulta v Hradci Králové
publication
New insights in bilirubin metabolism and their clinical implications
2013 |
3. lékařská fakulta
publication
Genome-wide association study to characterize serum bilirubin elevations in patients with HCV treated with GS-9256, an HCV NS3 serine protease inhibitor
2014 |
1. lékařská fakulta
publication
The impact of individual cytochrome P450 enzymes on oxidative metabolism of benzo[a]pyrene in human livers
2016 |
Přírodovědecká fakulta
publication
Benzo[a]pyrene-Induced Genotoxicity in Rats Is Affected by Co-Exposure to Sudan I by Altering the Expression of Biotransformation Enzymes
2021 |
Přírodovědecká fakulta
publication
Exposure to endocrine disruptors 17alpha-ethinylestradiol and estradiol influences cytochrome P450 1A1-mediated genotoxicity of benzo[a]pyrene and expression of this enzyme in rats
2018 |
Přírodovědecká fakulta
publication
Ellipticine oxidation and DNA adduct formation in human hepatocytes is catalyzed by human cytochromes P450 and enhanced by cytochrome b5
2012 |
Přírodovědecká fakulta
publication
Association between exposure-relevant polymorphisms in CYP1B1,EPHX1,NQ01,GSTM1,GSTP1 and GSTT1 and risk of colorectal cancer in a Czech population
2010 |
2. lékařská fakulta, 1. lékařská fakulta
publication
Expression Levels of Enzymes Metabolizing an Anticancer Drug Ellipticine Determined by Electromigration Assays Influence its Cytotoxicity to Cancer Cells - A Comparative Study
2014 |
Přírodovědecká fakulta, 2. lékařská fakulta
publication
Identification of Enzymes Oxidizing the Tyrosine Kinase Inhibitor Cabozantinib: Cabozantinib Is Predominantly Oxidized by CYP3A4 and Its Oxidation Is Stimulated by cyt b(5) Activity
2020 |
Přírodovědecká fakulta
publication
RNA expression of cytochrome P450 in breast cancer patients
2007 |
2. lékařská fakulta, 1. lékařská fakulta, Ústřední knihovna
publication
Genetic heterogeneity and minor CYP1B1 involvement in the molecular basis of primary congenital glaucoma in Gypsies
2008 |
2. lékařská fakulta
publication
RNA expression of cytochrome P450 in breast cancer patients
2007 |
2. lékařská fakulta
publication
Electrochemical Determination of Enzymes Metabolizing Ellipticine in Thyroid Cancer Cells - a Tool to Explain the Mechanism of Ellipticine Toxicity to these Cells
2013 |
Přírodovědecká fakulta, 2. lékařská fakulta
publication
Electrochemical Determination of Enzymes Metabolizing Ellipticine in Thyroid Cancer Cells - a Tool to Explain the Mechanism of Ellipticine Toxicity to these Cells
2013 |
Publikace bez příslušnosti k fakultě
publication
CYP1B1 gene polymorphism modifies pancreatic cancer risk but not survival
2010 |
1. lékařská fakulta
publication
Cytochrome P450-and peroxidase-mediated oxidation of anticancer alkaloid ellipticine dictates its anti-tumor efficiency
2011 |
Přírodovědecká fakulta
publication
Metabolic Gene Variants Associated with Chromosomal Aberrations in Healthy Humans
2015 |
2. lékařská fakulta, 1. lékařská fakulta
publication
A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches
2015 |
Přírodovědecká fakulta
publication
Clinical correlation of lymphovascular invasion and Silva pattern of invasion in early-stage endocervical adenocarcinoma: proposed binary Silva classification system
2022 |
1. lékařská fakulta
publication
MILACC study: could undetected lymph node micrometastases have impacted recurrence rate in the LACC trial?
2023 |
1. lékařská fakulta