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publication
Dinaciclib, a cyclin-dependent kinase inhibitor, is a substrate of human ABCB1 and ABCG2 and an inhibitor of human ABCC1 in vitro
2015 |
Farmaceutická fakulta v Hradci Králové
publication
Importance of ABCC1 for cancer therapy and prognosis
2014 |
1. lékařská fakulta, Lékařská fakulta v Plzni
publication
Encorafenib Acts as a Dual-Activity Chemosensitizer through Its Inhibitory Effect on ABCC1 Transporter In Vitro and Ex Vivo
2022 |
Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové
publication
Non-Coding Polymorphisms in Nucleotide Binding Domain 1 in ABCC1 Gene Associate with Transcript Level and Survival of Patients with Breast Cancer
2014 |
1. lékařská fakulta, 2. lékařská fakulta, 3. lékařská fakulta
publication
Interactions of cyclin-dependent kinase inhibitors AT-7519, flavopiridol and SNS-032 with ABCB1, ABCG2 and ABCC1 transporters and their potential to overcome multidrug resistance in vitro
2015 |
Farmaceutická fakulta v Hradci Králové
publication
Talazoparib Does Not Interact with ABCB1 Transporter or Cytochrome P450s, but Modulates Multidrug Resistance Mediated by ABCC1 and ABCG2: An in Vitro and Ex Vivo Study
2022 |
Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové
publication
Alisertib shows negligible potential for perpetrating pharmacokinetic drug-drug interactions on ABCB1, ABCG2 and cytochromes P450, but acts as dual-activity resistance modulator through the inhibition of ABCC1 transporter
2022 |
Farmaceutická fakulta v Hradci Králové
publication
Tazemetostat synergistically combats multidrug resistance by the unique triple inhibition of ABCB1, ABCC1, and ABCG2 efflux transporters in vitro and ex vivo
2023 |
Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové
publication
In vitro function and in situ localization of Multidrug Resistance-associated Protein (MRP)1 (ABCC1) suggest a protective role against methyl mercury-induced oxidative stress in the human placenta
2020 |
Farmaceutická fakulta v Hradci Králové
publication
Physicochemistry shapes bioactivity landscape of pan-ABC transporter modulators: Anchor point for innovative Alzheimer's disease therapeutics
2022 |
Publikace bez příslušnosti k fakultě
publication
ABC transporters are predictors of treatment failure in acute myeloid leukaemia
2024 |
1. lékařská fakulta, Přírodovědecká fakulta
publication
Modulation of bilirubin neurotoxicity by the Abcb1 transporter in the Ugt1(-/-) lethal mouse model of neonatal hyperbilirubinemia
2017 |
1. lékařská fakulta
publication
The expression profile of ATP-binding cassette transporter genes in breast carcinoma
2013 |
1. lékařská fakulta, Ústřední knihovna
publication
Cyclin-dependent kinase inhibitors AZD5438 and R547 show potential for enhancing efficacy of daunorubicin-based anticancer therapy: Interaction with carbonyl-reducing enzymes and ABC transporters
2019 |
Farmaceutická fakulta v Hradci Králové
publication
Interactions of Alectinib with Human ATP-Binding Cassette Drug Efflux Transporters and Cytochrome P450 Biotransformation Enzymes: Effect on Pharmacokinetic Multidrug Resistance
2019 |
Farmaceutická fakulta v Hradci Králové
publication
Entrectinib reverses cytostatic resistance through the inhibition of ABCB1 efflux transporter, but not the CYP3A4 drug-metabolizing enzyme
2020 |
Farmaceutická fakulta v Hradci Králové
publication
Isocitrate dehydrogenase 2 inhibitor enasidenib synergizes daunorubicin cytotoxicity by targeting aldo-keto reductase 1C3 and ATP-binding cassette transporters
2022 |
Farmaceutická fakulta v Hradci Králové
publication
The association of taxane resistance genes with the clinical course of ovarian carcinoma
2013 |
1. lékařská fakulta, 2. lékařská fakulta
publication
Germline and somatic genetic variability of oxysterol-related genes in breast cancer patients with early disease of the luminal subtype
2022 |
1. lékařská fakulta, Lékařská fakulta v Plzni, 2. lékařská fakulta
publication
Dabrafenib inhibits ABCG2 and cytochrome P450 isoenzymes; potential implications for combination anticancer therapy
2022 |
Farmaceutická fakulta v Hradci Králové
publication
Differences in Transcript Levels of ABC Transporters Between Pancreatic Adenocarcinoma and Nonneoplastic Tissues
2013 |
1. lékařská fakulta, Ústřední knihovna
publication
Bruton's Tyrosine Kinase Inhibitor Zanubrutinib Effectively Modulates Cancer Resistance by Inhibiting Anthracycline Metabolism and Efflux
2022 |
Farmaceutická fakulta v Hradci Králové
publication
Brivanib Exhibits Potential for Pharmacokinetic Drug-Drug Interactions and the Modulation of Multidrug Resistance through the Inhibition of Human ABCG2 Drug Efflux Transporter and CYP450 Biotransformation Enzymes
2019 |
Farmaceutická fakulta v Hradci Králové
publication
Multidrug Resistance Modulation Activity of Silybin Derivatives and Their Anti-inflammatory Potential
2020 |
Lékařská fakulta v Plzni
publication
The role of ABC transporters in progression and clinical outcome of colorectal cancer
2012 |
1. lékařská fakulta, Lékařská fakulta v Plzni