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aristolochic acid I
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publication
CYP1A1/2 and prostaglandin H synthase catalyze reductive activation of inflammatory drug aristolochic acid and that results in DNA adduct formation
2000 |
1. lékařská fakulta, Matematicko-fyzikální fakulta
publication
Co-Exposure to Aristolochic Acids I and II Increases DNA Adduct Formation Responsible for Aristolochic Acid I-Mediated Carcinogenicity in Rats
2021 |
Přírodovědecká fakulta
publication
Is aristolochic acid a risk for Balkan endemic nephropathy-associated urothelial cancer?
2002 |
Přírodovědecká fakulta
publication
Enzymes Metabolizing Aristolochic Acid and their Contribution to the Development of Aristolochic Acid Nephropathy and Urothelial Cancer
2013 |
Přírodovědecká fakulta
publication
Aristolochic acid as a probable human cancer hazard in herbal remedies: a review
2002 |
Přírodovědecká fakulta
publication
Role of cytochromes P450 in metabolism of carcinogenic aristolochic acid I: evidence of their contribution to aristolochic acid I detoxication and activation in rat liver
2011 |
Přírodovědecká fakulta, 1. lékařská fakulta, Fakulta tělesné výchovy a sportu
publication
Metabolická aktivace karcinogenní aristolochové kyseliny, rizikový faktor nádorů urothelia
2007 |
Přírodovědecká fakulta
publication
Balkan Endemic Nephropathy and the Causative Role of Aristolochic Acid
2019 |
Přírodovědecká fakulta
publication
Exceptionally long- term persistence of DNA adducts formed by carcinogenic aristolochic acid I in renal tissue from patients with aristolochic acid nephropathy
2014 |
Přírodovědecká fakulta
publication
Cancerogenic and nephrotoxic aristolochic acids are activated by human cytochromes P450 1A1 and 1A: study on enzyme-aristolochic acid molecular interactions
2002 |
Přírodovědecká fakulta
publication
Role of cytochromes P450 in metabolism of carcinogenic aristolochic acid I: evidence of their contribution to aristolochic acid I detoxication and activation in rat liver
2011 |
2. lékařská fakulta
publication
Carcinogenic aristolochic acids are activated by DT-diaphorase: 32P-postlabeling analysis of DNA aducts formation
2001 |
Přírodovědecká fakulta
publication
Carcinogenic aristolochic acid upon activation by DT-diaphorase form adducts found in DNA of patients with Chinese herbs neprophathy
2002 |
Přírodovědecká fakulta
publication
In vivo metabolism of aristolochic acid I and II in rats is influenced by their co-exposure
2020 |
Přírodovědecká fakulta
publication
The influence of ochratoxin A on DNA adduct formation by the carcinogen aristolochic acid in rats
2015 |
Přírodovědecká fakulta
publication
Carcinogenic and nephrotoxic alkaloids aristolochic acids are activated by D,T-diaphorase: 32P-postlabeling analysis of DNA adduct fomation
2001 |
Přírodovědecká fakulta
publication
Isolation of DT-diaphorase [NAD(P)H dehydrogenase (quinone)] from rat liver cytosol: identification of new substrates, carcinogenic aristolochic acids
2001 |
Přírodovědecká fakulta
publication
Evidence for reductive activation of carcinogenic aristolochic acids by prostaglandin H synthase - 32P-postlabeling analysis of DNA adduct formation
2001 |
Přírodovědecká fakulta
publication
Activities of enzymes activating carcinogenic aristolochic acid are influenced by components of pills used in treatement of patients with chinese herbs nephropathy
2002 |
Přírodovědecká fakulta
publication
Comparison of activation of aristolochic acid I and II with NADPH:quinone oxidoreductase, sulphotransferases and N-acetyltranferases
2011 |
Přírodovědecká fakulta
publication
Podíl biotransformačních enzymů na vývoji renální nedostatečnosti a nádorů močových cest způsobených aristolochovou kyselinou: naléhavé otázky, obtížné odpovědi
2008 |
Přírodovědecká fakulta
publication
Carcinogenic and nephrotoxic alkaloids aristolochic acids upon activation by D,T-diaphorase from adducts found in DNA of patients with chinese herbs nephropathy
2001 |
Přírodovědecká fakulta
publication
Carcinogenic and nephrotoxic alkaloids aristolochic acids are activated by D,T-diaphorase: 32P-postlabeling analysis of DNA adduct formation
2001 |
Přírodovědecká fakulta
publication
A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches
2015 |
Přírodovědecká fakulta
publication
Lidské cytochromy P450 1A1 a 1A2 participují na detoxikaci karcinogenních aristolochových kyselin
2008 |
Přírodovědecká fakulta
publication
Theoretical investigation of differences in nitroreduction of aristolochic acid I by cytochromes P450 1A1, 1A2 and 1B1
2012 |
Přírodovědecká fakulta
publication
Isolation of rat hepatic D,T-diaphorase and study of its interaction with carcinogenic aristolochic acids
2001 |
Přírodovědecká fakulta
publication
The effect of aristolochic acid I on expression of NAD(P)H:quinone oxidoreductase in mice and rats-A comparative study
2014 |
Přírodovědecká fakulta
publication
Human enzymes involved in metabolic activation of carcinogenic aristolochic acids: evidence for reductive activation by cytochromes P450 1A1 and 1A2
2001 |
Přírodovědecká fakulta
publication
Knockout and humanized mice as suitable tools to identify enzymes metabolizing the human carcinogen aristolochic acid
2014 |
Přírodovědecká fakulta