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drug–drug interactions
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Studium
publication
Lékové interakce statinů: Překoná pitvastatin Achillovu slabinu?
2011 |
1. lékařská fakulta
publication
Entecavir Interacts with Influx Transporters hOAT1, hCNT2, hCNT3, but Not with hOCT2: The Potential for Renal Transporter-Mediated Cytotoxicity and Drug-Drug Interactions
2016 |
Farmaceutická fakulta v Hradci Králové
publication
MDR1 and BCRP Transporter-Mediated Drug-Drug Interaction between Rilpivirine and Abacavir and Effect on Intestinal Absorption
2017 |
Farmaceutická fakulta v Hradci Králové
publication
Potentially clinically significant drug-drug interactions in older patients admitted to the hospital: A cross-sectional study
2023 |
Farmaceutická fakulta v Hradci Králové
publication
Brivanib Exhibits Potential for Pharmacokinetic Drug-Drug Interactions and the Modulation of Multidrug Resistance through the Inhibition of Human ABCG2 Drug Efflux Transporter and CYP450 Biotransformation Enzymes
2019 |
Farmaceutická fakulta v Hradci Králové
publication
Impact of drug-drug interactions on phenobarbital pharmacokinetics in pediatric patients
2019 |
1. lékařská fakulta
publication
Alisertib shows negligible potential for perpetrating pharmacokinetic drug-drug interactions on ABCB1, ABCG2 and cytochromes P450, but acts as dual-activity resistance modulator through the inhibition of ABCC1 transporter
2022 |
Farmaceutická fakulta v Hradci Králové
publication
Paliperidon, antipsychotikum 2. generace: Účinnost, snášenlivost a lékové interakce
2007 |
3. lékařská fakulta
publication
Evaluation of drug-drug interactions at the level of hepatic excretion
Publikace bez příslušnosti k fakultě
publication
The pregnane X receptor gene-humanized mouse: A model for investigating drug-drug interactions mediated by cytochromes P450 3A
2007 |
1. lékařská fakulta
publication
The pregnane X receptor gene-humanized mouse: A model for investigating drug-drug interactions mediated by cytochromes P450 3A
2007 |
Fakulta tělesné výchovy a sportu
publication
Retrospective evaluation of an observational cohort by the Central and Eastern Europe Network Group shows a high frequency of potential drug-drug interactions among HIV-positive patients receiving treatment for coronavirus disease 2019 (COVID-19)
2022 |
1. lékařská fakulta, Lékařská fakulta v Plzni
publication
Lékové interakce statinů, jejich klinická závažnost a management
2011 |
Farmaceutická fakulta v Hradci Králové
publication
Renal handling of amphotericin B and amphotericin B-deoxycholate and potential renal drug-drug interactions with selected antivirals
2014 |
Farmaceutická fakulta v Hradci Králové
publication
Ribociclib shows potential for pharmacokinetic drug-drug interactions being a substrate of ABCB1 and potent inhibitor of ABCB1, ABCG2 and CYP450 isoforms in vitro
2018 |
Farmaceutická fakulta v Hradci Králové
publication
Antiepileptic drug interactions: A clinical case demonstration
2011 |
2. lékařská fakulta
publication
Influence of Amlodipine Enantiomers on Human Microsomal Cytochromes P450: Stereoselective Time-Dependent Inhibition of CYP3A Enzyme Activity
2017 |
Farmaceutická fakulta v Hradci Králové
publication
Multidrug and toxin extrusion proteins (MATE/SLC47); role in pharmacokinetics
2013 |
Farmaceutická fakulta v Hradci Králové
publication
Tepotinib Inhibits Several Drug Efflux Transporters and Biotransformation Enzymes: The Role in Drug-Drug Interactions and Targeting Cytostatic Resistance In Vitro and Ex Vivo
2021 |
Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové
publication
Monepantel induces hepatic cytochromes p450 in sheep in vitro and in vivo
2015 |
Farmaceutická fakulta v Hradci Králové
publication
Olomoucine II, but Not Purvalanol A, Is Transported by Breast Cancer Resistance Protein (ABCG2) and P-Glycoprotein (ABCB1)
2013 |
Farmaceutická fakulta v Hradci Králové
publication
Emtricitabine is a substrate of MATE1 but not of OCT1, OCT2, P-gp, BCRP or MRP2 transporters
2017 |
Farmaceutická fakulta v Hradci Králové
publication
Ensartinib (X-396) Effectively Modulates Pharmacokinetic Resistance Mediated by ABCB1 and ABCG2 Drug Efflux Transporters and CYP3A4 Biotransformation Enzyme
2020 |
Farmaceutická fakulta v Hradci Králové
publication
The metabolism of flubendazole in human liver and cancer cell lines
2018 |
Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové
publication
Interplay of drug transporters P-glycoprotein (MDR1), MRP1, OATP1A2 and OATP1B3 in passage of maraviroc across human placenta
2020 |
Farmaceutická fakulta v Hradci Králové
publication
Evaluation of the Potency of Anti-HIV and Anti-HCV Drugs to Inhibit P-Glycoprotein Mediated Efflux of Digoxin in Caco-2 Cell Line and Human Precision-Cut Intestinal Slices
2022 |
Farmaceutická fakulta v Hradci Králové
publication
Universal efavirenz determination in transport study, rat placenta perfusion and placenta lysate by HPLC-UV
2017 |
Farmaceutická fakulta v Hradci Králové
publication
Dabrafenib inhibits ABCG2 and cytochrome P450 isoenzymes; potential implications for combination anticancer therapy
2022 |
Farmaceutická fakulta v Hradci Králové
publication
Tazemetostat synergistically combats multidrug resistance by the unique triple inhibition of ABCB1, ABCC1, and ABCG2 efflux transporters in vitro and ex vivo
2023 |
Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové
publication
Talazoparib Does Not Interact with ABCB1 Transporter or Cytochrome P450s, but Modulates Multidrug Resistance Mediated by ABCC1 and ABCG2: An in Vitro and Ex Vivo Study
2022 |
Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové